what is tamoxifen used for in males
Three to 6-month period is used for adjuvant and neoadjuvant chemotherapy. Adjuvant treatment of early-stage HR breast cancer with tamoxifen for at least 5 years has been shown to reduce the recurrence rate by about half throughout the first 10 years and reduces breast cancer mortality by about 30 throughout the first 15 years.
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In the National Surgical Adjuvant Breast and Bowel Project NSABP B-24 trial tamoxifen reduced the likelihood of ipsilateral recurrence at five years from 9 - 6 and also reduced the risk of a tumor in the contralateral breast.
. J Clin Oncol 2014321365 Lancet 19993531993 Comment Here Reference. Once gynecomastia is diagnosed cosmetic surgery is often needed to correct the problem. Many anabolic steroid users will use anti-estrogens selective estrogen receptor modulators such as tamoxifen and clomiphene or anastrozole which is a nonsteroidal aromatase inhibitor to minimize side effects of estrogen and stimulate testosterone production.
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